Tìm theo
St. John's Wort
Thuốc Gốc
Small Molecule
ĐG : Guna Inc. , http://www.gunainc.com
Tương Tác Thuốc :
  • Alprazolam St. John's Wort may decrease the effect of the benzodiazepine, alprazolam.
  • Aminophylline St. John's Wort decreases the effect of theophylline
  • Amprenavir St. John's Wort decreases the effect of indinavir
  • Atazanavir St. John's Wort decreases the levels/effects of atazanavir
  • Axitinib Avoid combination due to the likely decreased levels of axitinib.
  • Boceprevir Strong CYP3A4 inducers will decrease levels of boceprevir. Concomitant therapy is contraindicated.
  • Cabazitaxel Concomitant therapy with a strong CYP3A inducer may decrease concentrations of cabazitaxel. Avoid concomitant therapy.
  • Cabozantinib Avoid combination. May decrease concentration of cabozantinib. Also avoid all other strong CYP3A4 inducers.
  • Citalopram St. John's Wort increases the effect and toxicity of the SSRI, citalopram.
  • Clonazepam St. John's Wort may decrease the effect of the benzodiazepine, clonazepam.
  • Cyclosporine St. John's Wort decreases the effect of cyclosporine
  • Delavirdine St. John's Wort decreases the antiretroviral effect
  • Desvenlafaxine Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
  • Diazepam St. John's Wort may decrease the effect of the benzodiazepine, diazepam.
  • Digoxin St. John's Wort decreases the effect of digoxin
  • Efavirenz St. John's Wort decreases the antiretroviral effect
  • Erlotinib Decreased levels/effect of erlotinib
  • Escitalopram St. John's Wort increases the effect and toxicity of the SSRI, escitalopram.
  • Estradiol valerate/Dienogest Affects CYP3A4 metabolism, decreases or effects levels of Estradiol valerate/Dienogest.
  • Ethinyl Estradiol St. John's Wort could reduce the contraceptive effect
  • Etravirine Etravirine may experience a decrease in serum concentration. It is recommended to avoid concurrent therapy.
  • Fluoxetine St. John's Wort increases the effect and toxicity of the SSRI, fluoxetine.
  • Fluvoxamine St. John's Wort increases the effect and toxicity of the SSRI, fluvoxamine.
  • Fosamprenavir St. John's Wort decreases the effect of indinavir
  • Gefitinib The CYP3A4 inducer, St. John's Wort, may decrease the serum concentration and therapeutic effects of gefitinib.
  • Imatinib St. John's Wort decreases levels of imatinib
  • Indinavir St. John's Wort decreases the effect of indinavir
  • Ivacaftor Strong CYP3A4 inducers may decrease levels of ivacaftor. Monitor concomitant therapy closely.
  • Methadone St. John's Wort decreases levels/effect of methadone
  • Midazolam St. John's Wort may decrease the effect of the benzodiazepine, midazolam.
  • Nefazodone St. John's Wort increases the effect and toxicity of the SSRI, nefazodone.
  • Nelfinavir St. John's Wort decreases the effect of indinavir
  • Nevirapine St. John's Wort decreases nevirapine effect
  • Nifedipine St. John's Wort decreases the effect of nifedipine
  • Norethindrone St. John's Wort could reduce the contraceptive effect
  • Omeprazole St. John's Wort decreases the levels/effects of omeprazole
  • Oxtriphylline St. John's Wort decreases the effect of theophylline
  • Paclitaxel Avoid combination due to potential decrease in serum concentration of paclitaxel.
  • Paroxetine St. John's Wort increases the effect and toxicity of the SSRI, paroxetine.
  • Perampanel Avoid combination due to the potential decrease in perampanel concentration.
  • Rasagiline Increased risk of toxicity with this association
  • Regorafenib Strong CYP3A4 inducers may decrease levels of regorafenib.
  • Roflumilast Affects CYP3A4 metabolism, decreases level or effect of roflumilast.
  • Tacrolimus St. John's Wort may decrease the blood concentration of Tacrolimus. Monitor for changes in the therapeutic/toxic effects of Tacrolimus if St. John's Wort therapy is initiated, discontinued or altered.
  • Temsirolimus St. John's Wort may increase the metabolism of Temsirolimus decreasing its efficacy. Concomitant therapy should be avoided.
  • Theophylline St. John's Wort decreases the effect of theophylline
  • Tipranavir St. John's Wort may decrease the concentration and efficacy of Tipranavir. Concomitant therapy should be avoided.
  • Tolvaptan St. John's Wort is a CYP3A4 inducer and will decrease serum concentrations of tolvaptan and ultimately, its clinical effects.
  • Tramadol Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
  • Tranylcypromine Increased risk of serotonin syndrome. Use caution during concomitant therapy and monitor for symptoms of serotonin syndrome.
  • Trazodone Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
  • Triazolam St. John's Wort may decrease the effect of the benzodiazepine, triazolam.
  • Trimipramine St. John's Wort may decrease serum concentrations of Trimipramine. Possible increased risk of serotonin syndrome. Monitor for changes in Trimipramine efficacy and toxicity if St. John's Wort is initiated, discontinued or dose changed.
  • Ulipristal Concomitant therapy with strong CYP3A4 inducers may decrease plasma concentrations of ulipristal and ultimately its effectiveness. Avoid combination therapy.
  • Vandetanib Decreases levels of vandetanib by affecting CYP3A4 metabolism. Contraindicated.
  • Venlafaxine Increased risk of serotonin syndrome. Monitor for symptoms of serotonin syndrome.
  • Voriconazole St. John's Wort may decrease the serum concentration of voriconazole by increasing its elimination. Concomitant therapy is contraindicated.
  • Warfarin St. John's Wort may decrease the serum concentration of warfarin by increasing its metabolism. Concomitant therapy should be avoided. Monitor for changes in the therapeutic and adverse effects of warfarin if St. John's Wort is initiated, discontinued or dose changed.
  • Zolmitriptan Use of two serotonin modulators, such as zolmitriptan and St. John's Wort, increases the risk of serotonin syndrome. Consider alternate therapy or monitor for serotonin syndrome during concomitant therapy.
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