Investigated for use/treatment in adverse effects (chemotherapy), cancer/tumors (unspecified), diabetic foot ulcers, lung cancer, solid tumors, and ulcers.

Investigated for use/treatment in melanoma.

Investigated for use/treatment in brain cancer, cancer/tumors (unspecified), lung cancer, and lymphoma (non-hodgkin's).

Investigated for use/treatment in addictions, dementia, parkinson's disease, schizophrenia and schizoaffective disorders, and strokes.

Investigated for use/treatment in colorectal cancer and solid tumors.

Investigated for use/treatment in leukemia (lymphoid).

Investigated for use/treatment in prostate cancer.

Investigated for use/treatment in asthma and crohn's disease.

Investigated for use/treatment in atherosclerosis and vascular diseases as a cardioprotective agent. Its use has also been suggested for the prevention of early restenosis ...

Investigated for use/treatment in tobacco dependence.

Investigated for use/treatment in adverse effects (chemotherapy) and adverse effects (drug).

Investigated for use/treatment in cancer/tumors (unspecified), gastric cancer, and pancreatic cancer.

Investigated for use/treatment in Alzheimer's disease and Parkinson's disease.

Investigated for use/treatment in gastric cancer.

Investigated for use/treatment in various forms of brain cancer; Malignant Glioma, Glioblastoma Multiforme, GBM, Anaplastic Astrocytoma, Oligo-Astrocytoma, Gliosarcoma

Investigated for use/treatment in colorectal cancer, hepatitis (viral, B), and lymphoma (non-hodgkin's). ISS 1018 is currently being investigated in combination with HBsAg vaccine...

Investigated for use/treatment in leukemia (myeloid).

Investigated for use/treatment in hepatitis (viral, C).

Investigated for use/treatment in cancer/tumors (unspecified) and ovarian cancer.

Investigated for use as a prodrug for Hepsera in treating hepatitis (viral, B).