For the treatment of various forms of cancer.

For treatment of non-Hodgkin's lymphoma, bone metastases, Paget's disease, and osteoporosis

Indicated as an adjunct for the prevention and treatment of wound sepsis in patients with second- and third-degree burns.

For the control of absence (petit mal) seizures that are refractory to other drugs.

B-cell non-Hodgkin's lymphoma

Rheumatoid arthritis and Chronic obstructive pulmonary disease

HIV infection

Chronic angina and Coronary Artery Disease

For the treatment of uterine fibroids and endometriosis.

Plasmin assists with the healing of minor burns, superficial wounds, ulcers, surgical wounds, and superficial hematomas

Post-menopausal women with osteoporosis

Cardiovascular Disorders and Atherosclerosis

Investigated for use/treatment in pain (acute or chronic).

Investigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.

For reduction of the frequency of relapses in patients with Relapsing-Remitting Multiple Sclerosis.

For the treatment of hypercalcemia. Also intended for the treatment of non-hodgkin's lymphoma.

Intended for the treatment of congestive heart failure and hyperuricemia.

Alzheimer's Disease

Atopic dermatitis