Investigated for use/treatment in melanoma, multiple myeloma, ovarian cancer, pancreatic cancer, and solid tumors.

For the topical treatment of actinic keratosis.

Investigated for use/treatment in crohn's disease, psoriasis and psoriatic disorders, and rheumatoid arthritis.

Investigated for use/treatment in fabry disease.

Investigated for use/treatment in breast cancer, ovarian cancer, and prostate cancer.

Investigated for use/treatment in amyotrophic lateral sclerosis (ALS), diabetes mellitus type 2, neurologic disorders, and neuropathy (diabetic).

Investigated for use/treatment in eye disorders/infections and strokes.

Investigated for use/treatment in cystic fibrosis and eye disorders/infections.

Investigated for use/treatment in breast cancer.

Investigated for use/treatment in congestive heart failure.

Investigated for use/treatment in hyperlipidemia, metabolic disease, and obesity.

Investigated for use/treatment in traumatic brain injuries.

For the long term, once-daily-dosing maintenance of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or ...

Investigated for use/treatment in obesity.

Investigated for use/treatment in pain (acute or chronic).

Fro the treatment of chronic bronchitis in adults.

Investigated for use/treatment in kidney disease.

Investigated for use/treatment in HIV infection and viral infection.

Investigated for use/treatment in hepatitis (viral, C) and parkinson's disease.