Tìm theo
Microplasmin
Thuốc Gốc
Small Molecule
CAS: 117698-25-6
Microplasmin is a truncated form of plasmin bound by alpha-2-antiplasmin. It is an enzyme that dissolves protein formations that are crucial to blood clot (thrombus) formation; similar protein formations are seen linking the vitreous to the retina in the eye. Microplasmin is a novel neuroprotective thrombolytic agent for the treatment of ischemic stroke.
Cơ Chế Tác Dụng : Microplasmin is a truncated form of plasmin bound by alpha-2-antiplasmin. It is an enzyme that dissolves protein formations that are crucial to blood clot (thrombus) formation; similar protein formations are seen linking the vitreous to the retina in the eye. Microplasmin is a novel neuroprotective thrombolytic agent for the treatment of ischemic stroke. Microplasmin is a direct acting thrombolytic as compared to most other thrombolytics which dissolve clots indirectly by activating the plasmin precursor, plasminogen (plasminogen activators - PAs). Microplasmin dissolves blood clots without the need for free plasminogen in the circulation. It dissolves blood clots by digesting fibrins.
Dược Động Học :

▧ Half Life :
4 seconds
Chỉ Định : Investigated for use/treatment in eye disorders/infections and strokes.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05028
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