Dược Lực Học :
KB2115 is liver selectuve TR agonist that can induce pharmacological effects in the liver. It increases energy consumption, reduces body weight and also markedly reduces blood lipids and blood glucose levels at doses not affecting heart rate, bone density or TSH levels.
Cơ Chế Tác Dụng :
KB2115 which is a compound with promising properties for treatment of obesity and dyslipidemia. KB2115 increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.
KB2115 works by selectively stimulating the thyroid hormone
receptor which is the protein in the body that mediates the effects of thyroid hormone. KB2115 has receptor and tissue selective properties and thereby negative effects on the heart can be avoided.
Chỉ Định :
Investigated for use/treatment in hyperlipidemia, metabolic disease, and obesity.