Dược Động Học :
▧ Protein binding :
▧ Metabolism :
Hepatic metabolism accounts for less than 30% of the biotransformation of most penicillins.
▧ Route of Elimination :
Nafcillin is primarily eliminated by nonrenal routes, namely hepatic inactivation and excretion in the bile.
▧ Half Life :
The serum half-life of nafcillin administered by the intravenous route ranged from 33 to 61 minutes as measured in three separate studies.