Magnesium

Khoáng chất và Vitamin

Thuốc Gốc

Small Molecule

CAS: 7439-95-4

ATC: A12CC08, B05XA11, A06AD03, B05XA10, A06AD19, A02AA04, A12CC09, A02AA01, A06AD02, A12CC01, A12CC04, B05CB03, A12CC07, G04BX01, A12CC03, A02AA03, A02AA02, A12CC05, A02AA05, A06AD01, A12CC06, A12CC30

ĐG : American Regent , http://www.americanregent.com

CTHH: Mg

PTK: 24.305

Magnesium hydroxide is used primarily in "Milk of Magnesia", a white aqueous, mildly alkaline suspension of magnesium hydroxide formulated at about 8%w/v. Milk of magnesia is primarily used to alleviate constipation, but can also be used to relieve indigestion and heartburn. When taken internally by mouth as a laxative, the osmotic force of the magnesia suspension acts to draw fluids from the body and to retain those already within the lumen of the intestine, serving to distend the bowel, thus stimulating nerves within the colon wall, inducing peristalsis and resulting in evacuation of colonic contents.

Nhận Dạng Quốc Tế & Đặc Tính Hóa Học

Công thức hóa học

Phân tử khối

24.305

Monoisotopic mass

23.985041898

InChI

InChI=1S/Mg/q+2

InChI Key

InChIKey=JLVVSXFLKOJNIY-UHFFFAOYSA-N

IUPAC Name

magnesium(2+) ion

Traditional IUPAC Name

magnesium

SMILES

[Mg++]

Độ tan chảy

651 °C

Độ sôi

1100 °C

logP

-0.57

Polarizability

1.78 Å³

Polar Surface Area (PSA)

Refractivity

Rotatable Bond Count

H Bond Acceptor Count

H Bond Donor Count

Physiological Charge

Number of Rings

Bioavailability

Rule of Five

true

Tương Tác Thuốc :

Alendronate Formation of non-absorbable complexes
Amprenavir The antiacid decreases the absorption of amprenavir
Atazanavir This gastric pH modifier decreases the levels/effects of atazanavir
Chloroquine The antiacid decreases the absorption of chloroquine
Ciprofloxacin Formation of non-absorbable complexes
Clodronate Formation of non-absorbable complexes
Dapsone Formation of non-absorbable complexes
Deferiprone Deferiprone serum concentrations may be decreased by magnesium salts.
Delavirdine Magnesium antacids may decrease the absorption of delavirdine.
Demeclocycline Formation of non-absorbable complexes
Dihydroquinidine barbiturate The antiacid decreases the absorption of quinidine
Doxycycline Formation of non-absorbable complexes
Enoxacin Formation of non-absorbable complexes
Etidronic acid Formation of non-absorbable complexes
Fosamprenavir The antiacid decreases the absorption of amprenavir
Gatifloxacin Formation of non-absorbable complexes
Gemifloxacin Formation of non-absorbable complexes
Grepafloxacin Magnesium may decrease the absorption of grepafloxacin. Doses should be spaced apart by at least 2 hours.
Ibandronate Formation of non-absorbable complexes
Indinavir Magnesium may decrease the absorption of indinavir.
Levofloxacin Formation of non-absorbable complexes
Lomefloxacin Formation of non-absorbable complexes
Methacycline Formation of non-absorbable complexes
Minocycline Formation of non-absorbable complexes
Moxifloxacin Formation of non-absorbable complexes
Norfloxacin Formation of non-absorbable complexes
Ofloxacin Formation of non-absorbable complexes
Oxytetracycline Formation of non-absorbable complexes
Pefloxacin Formation of non-absorbable complexes
Polystyrene sulfonate Risk of alkalosis in renal impairment
Quinidine Magnesium antacids may decrease the absorption of quindine.
Quinidine barbiturate The antiacid decreases the absorption of quinidine
Risedronate Formation of non-absorbable complexes
Rosuvastatin Magnesium-containing antacids may decrease the absorption of rosuvastatin.
Temafloxacin Formation of non-absorbable complexes
Tetracycline Formation of non-absorbable complexes
Trovafloxacin Formation of non-absorbable complexes

Liều Lượng & Cách Dùng : Aerosol - Oral
Capsule - Oral
Liquid - Intramuscular
Liquid - Intravenous
Liquid - Oral
Ointment - Topical
Pellet - Oral
Powder - Oral
Solution - Intramuscular
Solution - Intravenous
Solution - Oral
Solution / drops - Oral
Suspension - Oral
Syrup - Oral
Tablet - Oral

Dữ Kiện Thương Mại

Đóng gói

Công ty : American Regent

Website : http://www.americanregent.com
Công ty : American Therapeutics Medicines Inc.
Công ty : Bioniche Pharma

Website : http://www.bionichepharmausa.com
Công ty : Claris Lifesciences Inc.

Website : http://www.clarislifesciences.com
Công ty : DSM Corp.

Website : http://www.dsm.com
Công ty : Luitpold Pharmaceuticals Inc.

Website : http://www.luitpold.com
Công ty : Mallinckrodt Baker Inc.

Website : http://www.mallbaker.com
Công ty : McGuff Co. Inc.

Website : http://www.mcguff.com
Công ty : Merit Pharmaceuticals

Website : http://www.meritpharm.com
Công ty : Pekana Naturheilmittel GmbH

Website : http://www.pekana.com
Công ty : Torrance Co.

Website : http://www.torranceco.com
Công ty : United Guardian Inc.

Website : http://www.u-g.com

Tài Liệu Tham Khảo Thêm

drugbank

http://www.drugbank.ca/drugs/DB01378

PubChem Compound

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=888

PubChem Substance

http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508750

KEGG Compound

http://www.genome.jp/dbget-bin/www_bget?cpd:C00305

ChemSpider

http://www.chemspider.com/Chemical-Structure.865.html

BindingDB

http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=15

PharmGKB

http://www.pharmgkb.org/drug/PA450287

Wikipedia

http://en.wikipedia.org/wiki/Magnesium

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