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4 amino 4 deoxypteroylglutamate, 4 amino pga, 4 aminofolic acid
Prior to its withdrawal, aminopterin was initially used in the treatment of childhood leukemia; specifically to induce remissions. Later, aminopterin was used off-label in the ...
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z 2 cyano alpha alpha alpha trifluoro 3 hydroxy p crotonotoluidide, a 77 1726, a 771726
Used in the treatment of relapsing forms of multiple sclerosis (MS).
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braf v600e kinase inhibitor ro5185426, plx4032, zelboraf
Treatment of unresectable or metastatic melanoma in patients with the BRAF-V600 mutation.
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r 8 3 aminopiperidin 1 yl 7 but 2 ynyl 3 methyl 1 4 methylquinazolin 2 ylmethyl 3 7 dihydro purine 2 6 dione, bi 1356, bi 1356
Linagliptin is used for the management of type 2 diabetes mellitus.
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3 2 cyanophenyl 5 2 pyridyl 1 phenyl 1 2 dihydropyridin 2 one, e 2007, e2007
Used in patients over 12 years old for the treatment of partial-onset seizures that may or may not occur with generalized seizures.
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cys cys glu tyr cys cys asn pro ala cys thr gly cys tyr disulfide bridge 1 6 2 10 5 13, l cysteinyl l cysteinyl l alpha glutamyl l tyrosyl l cysteinyl l cysteinyl l asparaginyl l prolyl l alanyl l cysteinyl l threonylglycyl l cysteinyl l tyrosine cyclic 1 6 2 10 5 13 tris disulfide, linzess
Treatment of irritable bowel syndrome (IBS) with constipation and chronic idiopathic constipation.
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r 4 amino 3 4 chlorophenyl butan oic acid, r baclofen, os440
Investigated in clinical trials as a potential treatment for spasticity in multiple sclerosis, autism spectrum disorder, and social withdrawal in fragile X syndrome.
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carboxypeptidase g2, folate hydrolase g2, glutamate carboxypeptidase
Used in patients on methotrexate treatment who have kidney dysfunction, and are experiencing an abnormally high plasma concentration of methotrexate (> 1 micromole per liter).
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gly2 glp 2, alx 0600, alx 0600
Treatment of short bowel syndrome (SBS), malabsorption associated with the removal of the intestine, in adults patients who are dependent on parenteral support.
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ap 24534, ap24534, ponatinibum
Ponatinib is indicated for the treatment of adult patients with chronic phase, accelerated phase, or blast phase chronic myeloid leukemia (CML) that is resistant or intolerant to ...
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1 6 bromo 2 methoxy quinolin 3 yl 4 dimethylamino 2 naphthalen 1 yl 1 phenyl butan 2 ol, bedaquilina, bedaquilinum
Bedaquiline is indicated as part of combination therapy in adults (≥ 18 years) with pulmonary multi-drug resistant tuberculosis (MDR-TB).
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4 hydroxy 4 androstene 3 17 dione, 4 hydroxy delta 4 androstenedione, 4 hydroxy 4 androstenedione
For the treatment of estrogen-receptor positive breast cancer in post-menopausal women.
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1 glucopyranosyl 4 methyl 3 5 4 fluorophenyl 2 thienylmethyl benzene, canagliflozin hydrate
Canagliflozin is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. Use in type 1 diabetes mellitus patients or in ...
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e but 2 enedioic acid dimethyl ester, 1 2 bis methoxycarbonyl trans ethylene, bg 12
Used in multiple sclerosis patients with relapsing forms.
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gsk 1120212, jtp 74057, trametinib dimethyl sulfoxide
Trametinib is indicated for the treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test.
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dabrafenib, gsk2118436a
Dabrafenib is indicated for the treatment of patients with unresectable or metastatic melanoma with BRAF V600E mutation as detected by an FDA-approved test.
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radium 223 chloride, radium 223 dichloride, xofigo
Used in patients who have metastatic bone cancer that is symptomatic with no visceral metastases and patients who have prostate cancer that is castration resistant.
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afatinibum, bibw 2992
Afatinib is a kinase inhibitor indicated for the first-line treatment of patient with metastatic non-small cell lung cancer (NSCLC) whose tumours have epidermal growth factor ...
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f 2695, levomilnacipran
Levomilnacipran is a serotonin and norepinephrine reuptake inhibitor and is indicated for the treatment of major depressive disorder (MDD).
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cis z 4 3 2 chlorothioxanthen 9 ylidene propyl 1 piperazineethanol decanoate, clopixol depot, decanoic acid 2 4 3 2 chloro 9h thioxanthen 9 ylidene propyl 1 piperazinyl ethyl ester z
Indicated for longer term maintenance therapy of schizophrenic episodes.