Dược Động Học :
▧ Absorption :
Following a single subcutaneous dose of peginterferon alfa-2b, the mean absorption half-life (t½ ka) was 4.6 hours.
▧ Route of Elimination :
Renal elimination accounts for 30% of the clearance.
▧ Half Life :
The mean elimination half-life is approximately 40 hours (range 22 to 60 hours) in patients with HCV infection.
▧ Clearance :
* Oral cl=22 mL/hr∙kg [patients with HCV infection]