Tìm theo
Hyaluronidase
Các tên gọi khác (5 ) :
  • HYAL-1
  • Hyaluronidase 1 precursor
  • Hyaluronidase PH-20
  • Sperm adhesion molecule 1
  • Sperm surface protein PH-20
Máu, Chế phẩm máu & Dung dịch cao phân tử
Thuốc Gốc
Biotech
CAS: 488712-31-8
ATC: B06AA03
ĐG : Akorn Inc. , http://www.akorn.com
CTHH: C2455H3775N617O704S21
PTK: 53870.9000
Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C2455H3775N617O704S21
Phân tử khối
53870.9000
Độ kỵ nước
-0.117
Điểm đẳng điện tích
5.73
Dược Lực Học : Hyaluronidase hydrolyzes hyaluronic acid and increase diffusion of injected drugs, thus facilitating their absorption. Hyaluronidase is used for enhancing absorption and distribution of other injected drugs.
Cơ Chế Tác Dụng : Highly purified sheep hyaluronidase for administration by injection into the vitreous of the eye. Hyaluronidase is a spreading or diffusing substance. It increase the permeability of connective tissue through the hydrolysis of hyaluronic acid. Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and increases diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption.
Chỉ Định : For increase of absorption and distribution of other injected drugs and for rehydration.
Tương Tác Thuốc :
  • Dopamine Consider modifying therapy due to enhanced adverse effects of dopamine.
  • Phenylephrine Avoid combination because hyaluronidase can potentiate the vasoconstrictive effect of phenylephrine.
Dữ Kiện Thương Mại
Giá thị trường
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Vitragan
  • Công ty : Ista Pharma
    Sản phẩm biệt dược : Vitrase
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00070
National Drug Code Directory
http://www.hipaaspace.com/Medical_Billing/Coding/National.Drug.Codes/PDF/0548-9090-10
GenBank
http://www.ncbi.nlm.nih.gov/nuccore/L13781
PharmGKB
http://www.pharmgkb.org/drug/PA164745713
Wikipedia
http://en.wikipedia.org/wiki/Hyaluronidase
RxList
http://www.rxlist.com/cgi/generic/hylenex.htm
Drugs.com
http://www.drugs.com/cdi/hyaluronidase.html
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