Tìm theo
Attapulgite
Thuốc đường tiêu hóa
Thuốc Gốc
Small Molecule
CAS: 12174-11-7
ATC: A07BC04
Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Until 2003, it was the active ingredient used in Kaopectate, before that product was reformulated with bismuth subsalicylate.
Dược Lực Học : Attapulgite is an adsorptive magnesium aluminium phyllosilicate which binds to toxins, bacteria and water.
Cơ Chế Tác Dụng : Attapulgite is a magnesium aluminium phyllosilicate which occurs in a type of clay soil common to the Southeastern United States. When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Until 2003, it was the active ingredient used in Kaopectate, before that product was reformulated with bismuth subsalicylate. Attapulgite adsorbs water, toxins and bacteria, contributing to firmer stools, reducing fluid loss from diarrhea.
Chỉ Định : When used in medicine, it physically binds to acids and toxic substances in the stomach and digestive tract. For that reason, it has often been used in antidiarrheal medications. Attapulgite is an adsorbent.
Tương Tác Thuốc :
  • Chloroquine The antiacid decreases the absorption of chloroquine
  • Clindamycin The aluminium salt decreases the absorption of lincosamides
  • Demeclocycline Formation of non-absorbable complexes
  • Doxycycline Formation of non-absorbable complexes
  • Lincomycin The aluminium salt decreases the absorption of lincosamides
  • Minocycline Formation of non-absorbable complexes
  • Penciclovir The multivalent agent decreases the effect of penicillamine
  • Tetracycline Formation of non-absorbable complexes
Liều Lượng & Cách Dùng : Suspension - Oral
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01574
PharmGKB
http://www.pharmgkb.org/drug/PA164781017
Wikipedia
http://en.wikipedia.org/wiki/Attapulgite
Drugs.com
http://www.drugs.com/cdi/attapulgite.html
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