Dược Động Học :
▧ Absorption :
Rapidly absorbed by the small intestine with an oral bioavailability of 20%.
▧ Metabolism :
Hepatic. Ximelagatran is a prodrug, being converted in vivo to the active agent melagatran. This conversion takes place in the liver and many other tissues through dealkylation and dehydroxylation (replacing the ethyl and hydroxyl groups with hydrogen).
▧ Half Life :