Urea
Thuốc điều trị bệnh da liễu
Thuốc Gốc
Small Molecule
CAS: 57-13-6
ĐG :
A. Aarons Inc.
, http://www.aaronindustriesinc.com
CTHH: CH4N2O
PTK: 60.0553
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
CH4N2O
Phân tử khối
60.0553
Monoisotopic mass
60.03236276
InChI
InChI=1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)
InChI Key
InChIKey=XSQUKJJJFZCRTK-UHFFFAOYSA-N
IUPAC Name
urea
Traditional IUPAC Name
urea
SMILES
NC(N)=O
Độ tan chảy
132.7 °C
Độ hòa tan
5.45E+005 mg/L (at 25 °C)
logP
-2.11
logS
0.96
pKa (strongest acidic)
15.73
pKa (Strongest Basic)
-2.4
PSA
69.11 Å2
Refractivity
13.14 m3·mol-1
Polarizability
5.1 Å3
Rotatable Bond Count
0
H Bond Acceptor Count
1
H Bond Donor Count
2
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Rule of Five
true
caco2 Permeability
-5.34
pKa
0.1 (at 21 °C)
Dược Lực Học :
Chỉ Định :
[Patient Self Care, 2010]
- 10% hydrate skin
- 15% accelerate fibrin degradation
- 20-30% are antipruritic, break down keratin, decrease the thickness of the stratum corneum and are used in scaling conditions such as ichthysosis
- 40% are proteolytic and may be used to dissolve and peel dystrophic nails
[Patient Self Care, 2010]
Tương Tác Thuốc :
- Treprostinil Additive hypotensive effect. Monitor antihypertensive therapy during concomitant use.
Dữ Kiện Thương Mại
Đóng gói
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Công ty : A. Aarons Inc.Website : http://www.aaronindustriesinc.com
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Công ty : Pegasus Laboratories Inc.Website : http://www.pegasuslabs.com
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Công ty : Perrigo Co.Website : http://www.perrigo.com
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Công ty : Pharma Pac LLCWebsite : http://www.pharmapacllc.com
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Công ty : PharmadermWebsite : http://www.pharmaderm.com
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Công ty : Physicians Total Care Inc.Website : http://www.physicianstotalcare.com
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Công ty : Prasco LabsWebsite : http://www.prasco.com
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Website : http://www.pccarx.com
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Công ty : QualitestWebsite : http://www.worldoftest.com
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Công ty : Quinnova PharmaceuticalsWebsite : http://www.quinnova.com
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Website : http://www.sheffield-pharmaceuticals.com
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Công ty : Taro Pharmaceuticals USAWebsite : http://www.tarousa.com
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Công ty : Truett LaboratoriesWebsite : http://www.truettlabs.com
Tài Liệu Tham Khảo Thêm
drugbank
PubChem Compound
PubChem Substance
KEGG Compound
National Drug Code Directory
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