Tìm theo
UCB 44212
Thuốc Gốc
Small Molecule
CTHH: C10H14F2N2O2
PTK: 232.2272
UCB 44212 is indicated for the treatment of various types seizure disorders such as epilepsy, a neurological dysfunction in which excessive surges of electrical energy are emitted in the brain, and other disorders.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H14F2N2O2
Phân tử khối
232.2272
Monoisotopic mass
232.102334112
InChI
InChI=1S/C10H14F2N2O2/c1-2-7(10(13)16)14-5-6(3-8(11)12)4-9(14)15/h3,6-7H,2,4-5H2,1H3,(H2,13,16)/t6-,7+/m1/s1
InChI Key
InChIKey=ANWPENAPCIFDSZ-RQJHMYQMSA-N
IUPAC Name
(2S)-2-[(4S)-4-(2,2-difluoroethenyl)-2-oxopyrrolidin-1-yl]butanamide
Traditional IUPAC Name
seletracetam
SMILES
CC[C@H](N1C[C@@H](CC1=O)C=C(F)F)C(N)=O
Độ hòa tan
1.02e+00 g/l
logP
0.091
logS
-2.4
pKa (strongest acidic)
14.66
pKa (Strongest Basic)
-0.75
PSA
63.4 Å2
Refractivity
64.33 m3·mol-1
Polarizability
21.1 Å3
Rotatable Bond Count
4
H Bond Acceptor Count
2
H Bond Donor Count
1
Physiological Charge
0
Number of Rings
1
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Cơ Chế Tác Dụng : UCB 44212 is indicated for the treatment of various types seizure disorders such as epilepsy, a neurological dysfunction in which excessive surges of electrical energy are emitted in the brain, and other disorders. UCB 44212 is effective in controlling the seizures associated with epilepsy. Some anticonvulsants are thought to generally depress central nervous system (CNS) function. Others, such as GABA inhibitors, are thought to target specific neurochemical processes, suppress excess neuron function, and regulate electrochemical signals in the brain.
Chỉ Định : Investigated for use/treatment in epilepsy.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05885
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=9942725
ChemSpider
http://www.chemspider.com/Chemical-Structure.8118337.html
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