TST10088

Thuốc Gốc

Small Molecule

TST10088 is a recombinant variant of a plant toxin belonging to the family of class II ribosome inactivating proteins. These molecules efficiently kill cells by activating preprogrammed death pathways known as apoptosis. TST10088 has been designed and engineered by Twinstrand to contain a peptide switch that is specifically cleaved by the matrix metalloproteinases which are known to be involved in tumor growth and metastasis. Cleavage of the peptide switch activates the prodrug causing ribosomal inactivation and the death of cancerous cells.

Chỉ Định : Investigated for use/treatment in solid tumors.

Tài Liệu Tham Khảo Thêm

drugbank

http://www.drugbank.ca/drugs/DB05151

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