Cơ Chế Tác Dụng :
TRX1 is a humanized antibody that binds to the CD4 receptor found on a subset of T cells. TRX1 is being developed for the potential treatment of autoimmune diseases in collaboration with Genentech, Inc. TolerRx is currently conducting a Phase I clinical study of TRX1 in the United Kingdom.
TRX1 induces and maintains immunological tolerance and reprogram the immune system to treat patients with immune-related diseases. In preclinical studies, TRX1 therapy has been shown to induce long-term, antigen-specific tolerance without compromising normal immune function.
Chỉ Định :
Investigated for use/treatment in autoimmune diseases.