Tìm theo
TNX-355
Thuốc Gốc
Biotech
TNX-355 is a monoclonal antibody that binds to CD4 receptors on the surface of CD4-positive cells, preventing the entry of HIV particles into lymphocytes. It is the most-advanced antibody in development for the treatment of HIV/AIDS.
Cơ Chế Tác Dụng : TNX-355 is a monoclonal antibody that binds to CD4 receptors on the surface of CD4-positive cells, preventing the entry of HIV particles into lymphocytes. It is the most-advanced antibody in development for the treatment of HIV/AIDS. TNX-355 is a humanized viral-entry inhibitor monoclonal antibody that coats CD4-positive cells -- the primary target of HIV infection. By blocking viral entry into CD4, TNX-355 creates a hurdle for HIV different from entry inhibitors that target viral proteins or chemokine co-receptors.
Chỉ Định : Investigated for use/treatment in HIV infection.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05435
Wikipedia
http://en.wikipedia.org/wiki/Entry_inhibitors
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