Tìm theo
TASQ
Các tên gọi khác (1) :
  • tasquinimod
Thuốc Gốc
Small Molecule
CTHH: C10H8N2O
PTK: 172.1833
The quinoline-3-carboxamide anti-angiogenic agent, tasquinimod, enhances the anti-prostate cancer efficacy of androgen ablation and taxotere without effecting serum PSA directly in human xenografts
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H8N2O
Phân tử khối
172.1833
Monoisotopic mass
172.063662888
InChI
InChI=1S/C10H8N2O/c11-10(13)8-5-7-3-1-2-4-9(7)12-6-8/h1-6H,(H2,11,13)
InChI Key
InChIKey=BLTDCIWCFCUQCB-UHFFFAOYSA-N
IUPAC Name
quinoline-3-carboxamide
Traditional IUPAC Name
3-quinolinecarboxamide
SMILES
NC(=O)C1=CC2=CC=CC=C2N=C1
Độ hòa tan
1.78e+00 g/l
logP
0.98
logS
-2
pKa (strongest acidic)
13.81
pKa (Strongest Basic)
3.04
PSA
55.98 Å2
Refractivity
49.06 m3·mol-1
Polarizability
17.64 Å3
Rotatable Bond Count
1
H Bond Acceptor Count
2
H Bond Donor Count
1
Physiological Charge
0
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Chỉ Định : Investigated for use/treatment in prostate cancer.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05861
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=15561101
ChemSpider
http://www.chemspider.com/Chemical-Structure.10437676.html
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