Cơ Chế Tác Dụng :
TAK-390MR is an investigational for the treatment of acid related disorders.. TAK-390MR employs a new modified release (MR) technology on an enantiomer of lansoprazole.
Lansoprazole has an asymmetric sulfur in its chemical structure and is commercially marketed as a racemic mixture. Both the (R)- and (S)-enantiomers of lansoprazole inhibit acid formation in isolated canine parietal cells and (H'+'/K'+')-ATPase in canine gastric microsomes with nearly the same potency.
Chỉ Định :
Investigated for use/treatment in duodenal ulcers, gastric ulcers, gastroesophageal reflux disease (GERD), and gastrointestinal diseases and disorders (miscellaneous).
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