Dược Lực Học :
T487 is a small molecule chemokine receptor antagonist to correct or modify immune system responses. It binds selectively and potently to CXCR3.
Cơ Chế Tác Dụng :
T487 is a small molecule chemokine receptor antagonist to correct or modify immune system responses. It binds selectively and potently to CXCR3. The formulation is administered orally and has anti-inflammatory effects in conditions such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.
T487 binds selectively and potently to CXCR3.
Độc Tính :
Well-tolerated in clinical trials for psorasis.
Chỉ Định :
Investigated for use/treatment in inflammatory disorders
such as rheumatoid arthritis, inflammatory bowel disease and psoriasis.