Tìm theo
Succinic acid
Các tên gọi khác (18 ) :
  • 1,2-Ethanedicarboxylic acid
  • Acide butanedioique
  • Acide succinique
  • Acidum succinicum
  • Amber acid
  • Asuccin
  • Bernsteinsaeure
  • Bernsteinsaure
  • Butandisaeure
  • Butanedioic acid
  • Butanedionic acid
  • Dihydrofumaric acid
  • e363
  • Ethylenesuccinic acid
  • HOOC-CH2-CH2-COOH
  • Spirit of amber
  • Succinate
  • Succinic acid
dietary supplements, micronutrients, supplements
Thuốc Gốc
Small Molecule
CAS: 110-15-6
ĐG : Breckenridge Pharmaceuticals , http://www.bpirx.com
CTHH: C4H6O4
PTK: 118.088
A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851)
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C4H6O4
Phân tử khối
118.088
Monoisotopic mass
118.02660868
InChI
InChI=1S/C4H6O4/c5-3(6)1-2-4(7)8/h1-2H2,(H,5,6)(H,7,8)
InChI Key
InChIKey=KDYFGRWQOYBRFD-UHFFFAOYSA-N
IUPAC Name
butanedioic acid
Traditional IUPAC Name
succinic acid
SMILES
OC(=O)CCC(O)=O
Độ tan chảy
188 °C
Độ sôi
235 dec °C
Độ hòa tan
8.32E+004 mg/L (at 25 °C)
logP
-0.59
logS
-0.2
pKa (strongest acidic)
3.55
PSA
74.6 Å2
Refractivity
23.54 m3·mol-1
Polarizability
10.14 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
4
H Bond Donor Count
2
Physiological Charge
-2
Number of Rings
0
Bioavailability
1
Rule of Five
true
pKa
4.21 (at 25 °C)
Cơ Chế Tác Dụng : A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. It is also used in foods as a sequestrant, buffer, and a neutralizing agent. (Hawley's Condensed Chemical Dictionary, 12th ed, p1099; McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed, p1851) Succinate is an essential component of the Krebs or citric acid cycle and serves an electron donor in the production of fumaric acid and FADH2. It also has been shown to be a good "natural" antibiotic because of its relative acidic or caustic nature (high concentrations can even cause burns). Succinate supplements have been shown to help reduce the effects of hangovers by activating the degradation of acetaldehyde - a toxic byproduct of alcohol metabolism - into CO2 and H2O through aerobic metabolism. Succinic acid has been shown to stimulate neural system recovery and bolster the immune system. Claims have also been made that it boosts awareness, concentration and reflexes.
Độc Tính : Oral rat LD50: 2260 mg/kg
Chỉ Định : For nutritional supplementation, also for treating dietary shortage or imbalance
Liều Lượng & Cách Dùng : Liquid - Oral
Solution / drops - Oral
Dữ Kiện Thương Mại
Giá thị trường
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00139
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=1110
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505859
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00042
ChemSpider
http://www.chemspider.com/Chemical-Structure.1078.html
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=26121
PharmGKB
http://www.pharmgkb.org/drug/PA164747739
Wikipedia
http://en.wikipedia.org/wiki/Succinate
... loading
... loading