Tìm theo
SPL-7013
Các tên gọi khác (1) :
  • SPL7013
Thuốc Gốc
Small Molecule
CAS: 676271-69-5
SPL7013 is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. It is the active ingredient of VivaGel, a water-based vaginal microbicide gel.
Cơ Chế Tác Dụng : SPL7013 is a lysine-based dendrimer with naphthalene disulfonic acid surface groups. It is the active ingredient of VivaGel, a water-based vaginal microbicide gel. Dendrimers such as SPL7013 are polymers that contain a central core, interior branches, and terminal surface groups adapted to specific targets. SPL7013 has a polyanionic outer surface that provides for multiple target interactions. The active surface groups bind to gp120 proteins on HIV's surface, preventing CD4 receptor binding by healthy cells and thus blocking transmission of HIV to healthy cells.
Chỉ Định : Investigated for use/treatment in genital herpes and HIV prevention.
Liều Lượng & Cách Dùng : Gel - Intravaginal
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Vivagel
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05658
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