Tìm theo
Salicylamide
Các tên gọi khác (8 ) :
  • 2-Carbamoylphenol
  • 2-Carboxamidophenol
  • 2-Hydroxybenzamide
  • o-hydroxybenzamide
  • OHB
  • Salicilamida
  • Salicylamidum
  • Salicylic acid amide
anti inflammatory agents non steroidal
Thuốc Gốc
Small Molecule
CAS: 65-45-2
ATC: N02BA55, N02BA05
CTHH: C7H7NO2
PTK: 137.136
Salicylamide is the common name for the substance o-hydroxybenzamide, or amide of salicyl. Salicylamide is a non-prescription drug with analgesic and antipyretic properties. Its medicinal uses are similar to those of aspirin. Salicylamide is used in combination with both aspirin and caffeine in the over-the-counter pain remedies
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C7H7NO2
Phân tử khối
137.136
Monoisotopic mass
137.047678473
InChI
InChI=1S/C7H7NO2/c8-7(10)5-3-1-2-4-6(5)9/h1-4,9H,(H2,8,10)
InChI Key
InChIKey=SKZKKFZAGNVIMN-UHFFFAOYSA-N
IUPAC Name
2-hydroxybenzamide
Traditional IUPAC Name
salicylamide
SMILES
NC(=O)C1=CC=CC=C1O
Độ tan chảy
142 °C
Độ sôi
181.5 °C
Độ hòa tan
2060 mg/L (at 25 °C)
logP
1.28
logS
-1.2
pKa (strongest acidic)
8.21
pKa (Strongest Basic)
-1.8
PSA
63.32 Å2
Refractivity
37.12 m3·mol-1
Polarizability
13.22 Å3
Rotatable Bond Count
1
H Bond Acceptor Count
2
H Bond Donor Count
2
Physiological Charge
0
Number of Rings
1
Bioavailability
1
Rule of Five
true
pKa
8.37 (at 20 °C)
Độc Tính : Oral, rat LD50: 1890 mg/kg
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08797
Wikipedia
http://en.wikipedia.org/wiki/Salicylamide
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