Tìm theo
RP101
Các tên gọi khác (1) :
  • BVDU
Thuốc Gốc
Small Molecule
RP101 is targeted at preventing tumor cells from developing resistance to chemotherapy, one of the most challenging areas facing oncologists. RP101 would be used as a co-treatment with cytostatic drugs to give a broader range of chemotherapy treatment options, thereby extending survival periods and improving quality of life for the cancer patients.
Cơ Chế Tác Dụng : RP101 is targeted at preventing tumor cells from developing resistance to chemotherapy, one of the most challenging areas facing oncologists. RP101 would be used as a co-treatment with cytostatic drugs to give a broader range of chemotherapy treatment options, thereby extending survival periods and improving quality of life for the cancer patients. RP101 down-regulated uridine phosphorylase, a marker of poor prognosis, and APEX1, which is involved in DNA repair, and repressed Stat-3 and its target VEGF. Furthermore, RP101 activated antitumor immunity.
Chỉ Định : Investigated for use/treatment in adverse effects (chemotherapy), chemotherapy, and pancreatic cancer.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05041
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