Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Monoisotopic mass
229.183049741
InChI
InChI=1S/C16H23N/c1-3-9-15(10-4-1)16(11-5-2-6-12-16)17-13-7-8-14-17/h1,3-4,9-10H,2,5-8,11-14H2
InChI Key
InChIKey=FYOWWXMGDATDQY-UHFFFAOYSA-N
IUPAC Name
1-(1-phenylcyclohexyl)pyrrolidine
Traditional IUPAC Name
rolicyclidine
SMILES
C1CCN(C1)C1(CCCCC1)C1=CC=CC=C1
pKa (Strongest Basic)
10.78
Refractivity
73.05 m3·mol-1
Dược Lực Học :
Rolicyclidine is similar in effects to phencyclidine but is slightly less potent and has less stimulant effects. Instead it acts by inducing a sedative effect described as being somewhat similar to a barbiturate, but with additional PCP-like dissociative, anaesthetic and hallucinogenic effects.
Cơ Chế Tác Dụng :
Rolicyclidine (PCPy) is a dissociative anesthetic drug with hallucinogenic and sedative effects. Due to its similarity in effects to PCP, PCPy was placed into the Schedule I list of illegal drugs in the 1970s, although it has never been widely abused and is now little known.
Rolicyclidine works primarily as an NMDA receptor antagonist, which blocks the activity of the NMDA Receptor.
Chỉ Định :
Rolicyclidine has anesthetic properties and can induce a sedative effect.