Tìm theo
Quisqualate
excitatory amino acid agonists
Thuốc Gốc
Small Molecule
CTHH: C5H7N3O5
PTK: 189.1262
An agonist at two subsets of excitatory amino acid receptors, ionotropic receptors that directly control membrane channels and metabotropic receptors that indirectly mediate calcium mobilization from intracellular stores. The compound is obtained from the seeds and fruit of Quisqualis chinensis. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C5H7N3O5
Phân tử khối
189.1262
Monoisotopic mass
189.038570349
InChI
InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChI Key
InChIKey=ASNFTDCKZKHJSW-REOHCLBHSA-N
IUPAC Name
(2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
Traditional IUPAC Name
quisqualate
SMILES
N[C@@H](CN1OC(=O)NC1=O)C(O)=O
Độ hòa tan
5.36e+01 g/l
logP
-3.7
logS
-0.55
pKa (strongest acidic)
1.46
pKa (Strongest Basic)
8.56
PSA
121.96 Å2
Refractivity
36.51 m3·mol-1
Polarizability
15.39 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
5
H Bond Donor Count
3
Physiological Charge
-1
Number of Rings
1
Bioavailability
1
Rule of Five
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB02999
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=40539
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46509075
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=17660
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