Tìm theo
Quercetin
Các tên gọi khác (1) :
  • 3,5,7,3',4'-Pentahydroxyflavone
Thực phẩm tăng cường hệ miễn dịch
Thuốc Gốc
Small Molecule
CAS: 117-39-5
ĐG : V Sab Medical Labs Inc.
CTHH: C15H10O7
PTK: 302.2357
A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C15H10O7
Phân tử khối
302.2357
Monoisotopic mass
302.042652674
InChI
InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
InChI Key
InChIKey=REFJWTPEDVJJIY-UHFFFAOYSA-N
IUPAC Name
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
Traditional IUPAC Name
quercetin
SMILES
OC1=CC2=C(C(O)=C1)C(=O)C(O)=C(O2)C1=CC=C(O)C(O)=C1
Độ tan chảy
316.5 °C
Độ hòa tan
60 mg/L (at 16 °C)
logP
2.16
logS
-3.1
pKa (strongest acidic)
6.44
pKa (Strongest Basic)
-4
PSA
127.45 Å2
Refractivity
76.86 m3·mol-1
Polarizability
28.54 Å3
Rotatable Bond Count
1
H Bond Acceptor Count
7
H Bond Donor Count
5
Physiological Charge
-1
Number of Rings
3
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Cơ Chế Tác Dụng : A flavonol widely distributed in plants. It is an antioxidant, like many other phenolic heterocyclic compounds. Glycosylated forms include RUTIN and quercetrin. [PubChem] Quercetin is a specific quinone reductase 2 (QR2) inhibitor, an enzyme (along with the human QR1 homolog) which catalyzes metabolism of toxic quinolines. Inhibition of QR2 in plasmodium may potentially cause lethal oxidative stress. The inhibition of antioxidant activity in plasmodium may contribute to killing the malaria causing parasites.
Dữ Kiện Thương Mại
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04216
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=5280343
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506533
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00389
ChemSpider
http://www.chemspider.com/Chemical-Structure.4444051.html
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=7460
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