Tìm theo
Potassium Iodide
Các tên gọi khác (3) :
  • Kaliumiodid
  • KI
  • Potassium iodide
Thuốc Gốc
Small Molecule
CAS: 7681-11-0
CTHH: IK
PTK: 166.0028
Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
IK
Phân tử khối
166.0028
Monoisotopic mass
165.868175281
InChI
InChI=1S/HI.K/h1H;/q;+1/p-1
InChI Key
InChIKey=NLKNQRATVPKPDG-UHFFFAOYSA-M
IUPAC Name
potassium iodide
Traditional IUPAC Name
potassium iodide
SMILES
[K+].[I-]
logP
0.2
Polarizability
1.78 Å3
Polar Surface Area (PSA)
0
Refractivity
0
Rotatable Bond Count
0
H Bond Acceptor Count
0
H Bond Donor Count
0
Physiological Charge
1
Number of Rings
0
Bioavailability
1
Rule of Five
true
Dược Lực Học : It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.
Chỉ Định : Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : ThyroShield
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB06715
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=4875
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=99443267
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C08219
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D01016
ChemSpider
http://www.chemspider.com/Chemical-Structure.4709.html
Wikipedia
http://en.wikipedia.org/wiki/SSKI
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