Tìm theo
Porphobilinogen
Các tên gọi khác (3) :
  • 2-aminomethylpyrrol-3-acetic acid 4-propionic acid
  • 5-(Aminomethyl)-4-(carboxymethyl)-1H-pyrrole-3-propionic acid
  • PBG
Thuốc Gốc
Small Molecule
CAS: 487-90-1
CTHH: C10H13N2O4
PTK: 225.2212
Porphobilinogen is a pyrrole involved in porphyrin metabolism. It is generated by the enzyme ALA dehydratase, and converted into hydroxymethyl bilane by the enzyme porphobilinogen deaminase.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C10H13N2O4
Phân tử khối
225.2212
Monoisotopic mass
225.087531914
InChI
InChI=1S/C10H13N2O4/c11-4-8-7(3-10(15)16)6(5-12-8)1-2-9(13)14/h5H,1-4,11H2,(H,13,14)(H,15,16)
InChI Key
InChIKey=YPHQRHBJEUDWJW-UHFFFAOYSA-N
IUPAC Name
3-[5-(aminomethyl)-4-(carboxymethyl)pyrrol-3-yl]propanoic acid
Traditional IUPAC Name
porphobilinogen
SMILES
NCc1ncc(CCC(O)=O)c1CC(O)=O
Độ hòa tan
2.72e+00 g/l
logP
-3.4
logS
-1.9
pKa (strongest acidic)
2.92
pKa (Strongest Basic)
8.45
PSA
113.51 Å2
Refractivity
54.73 m3·mol-1
Polarizability
22.11 Å3
Rotatable Bond Count
6
H Bond Acceptor Count
6
H Bond Donor Count
3
Physiological Charge
-1
Number of Rings
1
Bioavailability
1
Rule of Five
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB02272
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=1021
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505854
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00931
Wikipedia
http://en.wikipedia.org/wiki/Porphobilinogen
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