Cơ Chế Tác Dụng :
PHX1149 is a novel orally administered inhibitor of DPP4 for the treatment of type 2 diabetes.
PHX1149 is a potent and selective inhibitor of DPP4, a serine protease that has emerged as an important target for the treatment of type 2 diabetes. Inhibiting DPP4 increases the physiological levels of regulatory peptides, such as GLP-1, an important modulator of insulin response and digestion.
Dược Động Học :
▧ Half Life :
10-13 hours
Chỉ Định :
Investigated for use/treatment in diabetes mellitus type 2.