Tìm theo
PH94B
Thuốc Gốc
Small Molecule
PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized anxiety disorder). It is a member of a new family of pharmaceutical compounds called vomeropherins.
Dược Lực Học : Vomeropherin compounds are directly delivered to the nasal passages using either a metered nasal spray or a metered nasal aerosol. By virtue of the chemoreceptor’s location in the nasal passages, direct connections to the hypothalamus and limbic system and the ability of our compounds to act locally, vomeropherins do not need to achieve systemic absorption and distribution. This provides a significant therapeutic advantage over traditional therapeutics targeted at the hypothalamus and limbic system that require access to systemic circulation and must cross the blood-brain barrier followed by uptake into the brain to exert effects.
Cơ Chế Tác Dụng : PH94B is being developed by Pherin Pharmaceuticals, Inc. for the treatment of social phobias (generalized anxiety disorder). It is a member of a new family of pharmaceutical compounds called vomeropherins. There is little information available on the mechanism of action of vomeropherins. These compounds are delivered to the nasal passages and bind to chemoreceptors that in turn affect the hypothalamus and the limbic system.
Dược Động Học :
▧ Absorption :
Absorbed following nasal administration.
Chỉ Định : Intended for the acute treatment of social phobia.
Liều Lượng & Cách Dùng : Aerosol - Nasal
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04968
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