Tìm theo
Perflubron emulsion
Thuốc Gốc
Small Molecule
CTHH: C8BrF17
PTK: 498.962
Perflubron emulsion (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C8BrF17
Phân tử khối
498.962
Monoisotopic mass
497.891192132
InChI
InChI=1S/C8BrF17/c9-7(22,23)5(18,19)3(14,15)1(10,11)2(12,13)4(16,17)6(20,21)8(24,25)26
InChI Key
InChIKey=WTWWXOGTJWMJHI-UHFFFAOYSA-N
IUPAC Name
1-bromo-1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,8-heptadecafluorooctane
Traditional IUPAC Name
perflubron
SMILES
FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)Br
Độ hòa tan
3.14e-02 g/l
logP
6.64
logS
-4.2
Refractivity
48.52 m3·mol-1
Polarizability
21.18 Å3
Polar Surface Area (PSA)
0
Rotatable Bond Count
7
H Bond Acceptor Count
0
H Bond Donor Count
0
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Cơ Chế Tác Dụng : Perflubron emulsion (Oxygent) is being developed as an intravascular oxygen carrier designed to augment oxygen delivery in surgical patients. Perflubron emulsion (Oxygent) maintains hemodynamic stability during major surgery, thereby potentially reducing or avoiding intraoperative transfusions of donor blood in major surgery.Perflubron emulsion has ability to enable patients to be physiologically stable and safe at lower intraoperative Hb levels.
Chỉ Định : Investigated for use/treatment in cardiac surgery, hemorrhage, and ileus.
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty :
    Sản phẩm biệt dược : Oxygent
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05791
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=9873
ChemSpider
http://www.chemspider.com/Chemical-Structure.9489.html
Wikipedia
http://en.wikipedia.org/wiki/Oxygent
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