Cơ Chế Tác Dụng :
PA mAb(ABthrax) is a human monoclonal antibody to Bacillus anthracis protective antigen that was discovered and developed by Human Genome Sciences. PA mAb has been shown to be effective in protecting against anthrax in multiple experimental models in animals. A single dose of PA mAb increases survival significantly in both rabbit and nonhuman primate models of inhalational anthrax.
PA mAb has the potential to provide significant protection against anthrax infections when given prophylactically, and may lessen the natural progression of anthrax infection and increase survival if given as a post-exposure treatment. PA mAb also may prevent and treat infections by antibiotic-resistant strains of anthrax.
Chỉ Định :
Investigated for use/treatment in anthrax exposure and bacterial infection.