Tìm theo
Oxybenzone
Các tên gọi khác (8 ) :
  • (2-Hydroxy-4-methoxyphenyl)phenylmethanone
  • 2-Benzoyl-5-methoxyphenol
  • 2-Hydroxy-4-methoxybenzophenone
  • 4-Methoxy-2-hydroxybenzophenone
  • 4-Methoxy-2-hydroxybenzophenone butyric acid
  • Benzophenone-3
  • Oxibenzona
  • Oxybenzonum
sunscreening agents
Thuốc Gốc
Small Molecule
CAS: 131-57-7
ĐG : Axia Medical Solutions LLC , http://www.axiamedical.net
CTHH: C14H12O3
PTK: 228.2433
Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C14H12O3
Phân tử khối
228.2433
Monoisotopic mass
228.07864425
InChI
InChI=1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
InChI Key
InChIKey=DXGLGDHPHMLXJC-UHFFFAOYSA-N
IUPAC Name
2-benzoyl-5-methoxyphenol
Traditional IUPAC Name
oxybenzone
SMILES
COC1=CC(O)=C(C=C1)C(=O)C1=CC=CC=C1
Độ tan chảy
65.5 °C
Độ sôi
155 °C at 5.00E+00 mm Hg
Độ hòa tan
1.28e-01 g/l
logP
3.79
logS
-3.2
pKa (strongest acidic)
8.07
pKa (Strongest Basic)
-4.8
PSA
46.53 Å2
Refractivity
65.08 m3·mol-1
Polarizability
23.96 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
3
H Bond Donor Count
1
Physiological Charge
0
Number of Rings
2
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Dược Lực Học : Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone.
Cơ Chế Tác Dụng : Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. It forms colorless crystals that are readily soluble in most organic solvents. It is used as an ingredient in sunscreen and other cosmetics because it absorbs UV-A ultraviolet rays. Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin.
Dược Động Học :

▧ Route of Elimination :
In vivo studies show oxybenzone is abosorbed transdermally (through the skin) and is excreted in the urine.
Chỉ Định : Used as an ingredient in sunscreen and other cosmetics.
Liều Lượng & Cách Dùng : Lotion - Topical
Dữ Kiện Thương Mại
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB01428
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=4632
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46508419
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C14285
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D05309
ChemSpider
http://www.chemspider.com/Chemical-Structure.4471.html
BindingDB
http://www.bindingdb.org/bind/chemsearch/marvin/MolStructure.jsp?monomerid=50253134
PharmGKB
http://www.pharmgkb.org/drug/PA164742933
Wikipedia
http://en.wikipedia.org/wiki/Oxybenzone
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