Tìm theo
OspA lipoprotein
Các tên gọi khác (1) :
  • Outer surface protein A precursor
Vaccine
Thuốc Gốc
Biotech
CTHH: C1198H2012N322O422S2
PTK: 27743.1000
Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C1198H2012N322O422S2
Phân tử khối
27743.1000
Độ kỵ nước
-0.652
Điểm đẳng điện tích
6.72
Dược Lực Học : OspA lipoprotein is a single polypeptide chain of 270 amino acids. It is a vaccination used to prevent Lyme Disease.
Cơ Chế Tác Dụng : Vaccine against Lyme disease that contains lipoprotein OspA, an outer surface protein of Borrelia burgdorferi sensu stricto ZS7, as expressed by Escherichia coli. Lipoprotein OspA is a single polypeptide chain of 257 amino acids with lipids covalently bonded to the N terminus. It is conjugated with alum (aluminum hydroxide) as an adjuvant. OspA lipoprotein, an outer surface protein of the bacteria Borrelia burgdorferi sensu stricto ZS7, is used to stimulate the production of specific antibodies against B. burgdorferi. It is used as a vaccination against Lyme Disease, a disease carried by ticks.
Dược Động Học :

▧ Half Life :
1.2 hours (mammalian reticulocytes, in vitro).
Chỉ Định : For prophylactic treatment of Lyme Disease
Dữ Kiện Thương Mại
Nhà Sản Xuất
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00045
GenBank
http://www.ncbi.nlm.nih.gov/nuccore/X16467
PharmGKB
http://www.pharmgkb.org/drug/PA164743058
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