NV1020

Thuốc điều trị ung thư

Thuốc Gốc

Biotech

NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic.

Cơ Chế Tác Dụng : NV1020, a genetically engineered herpes simplex virus, is a novel anticancer therapeutic. Cancer-killing viruses, so-called oncolytic viruses are specific herpes simplex viruses, or HSVs, generally known as the cause of cold sores. These viruses are used, however, in a modified and "disarmed" form in order to make them utilizable as a therapeutic agent in humans. This is achieved by switching off certain genes that normally enable the virus to multiply in healthy cells, which would destroy these cells. As a result of this genetic modification, the HSVs are able to reproduce in tumor cells solely, since only these offer an environment that compensates for the loss of the removed viral genes. Consequently, the virus is able to replicate in the tumor cells, selectively destroying them without harming healthy tissue.

Chỉ Định : Intended for the treatment of various forms of cancer.

Tài Liệu Tham Khảo Thêm

drugbank

http://www.drugbank.ca/drugs/DB04969

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