Cơ Chế Tác Dụng :
NBI-56418 is a proprietary, orally active small molecule Gonadotropin-Releasing Hormone (GnRH) receptor antagonist that could diminish bone demineralisation. It is being developed by Neurocrine Biosciences.
NBI-56418, is a specific highly potent non-peptide, orally active antagonist of the GnRH receptor. This compound inhibits pituitary luteinizing hormone (LH) secretion directly, potentially preventing the several week delay and flare associated with peptide agonist therapy.
Chỉ Định :
Investigated for use/treatment in endometriosis.