Tìm theo
Methyltrienolone
Các tên gọi khác (2) :
  • 17-beta-Hydroxy-17-methylestra-4,9,11-trien-3-one
  • Metribolone
Thuốc Gốc
Small Molecule
CAS: 965-93-5
CTHH: C19H24O2
PTK: 284.3927
A synthetic non-aromatizable androgen and anabolic steroid. It binds strongly to the androgen receptor and has therefore also been used as an affinity label for this receptor in the prostate and in prostatic tumors.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C19H24O2
Phân tử khối
284.3927
Monoisotopic mass
284.177630012
InChI
InChI=1S/C19H24O2/c1-18-9-7-15-14-6-4-13(20)11-12(14)3-5-16(15)17(18)8-10-19(18,2)21/h7,9,11,16-17,21H,3-6,8,10H2,1-2H3/t16-,17+,18+,19+/m1/s1
InChI Key
InChIKey=CCCIJQPRIXGQOE-XWSJACJDSA-N
IUPAC Name
(10S,11S,14S,15S)-14-hydroxy-14,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6,16-trien-5-one
Traditional IUPAC Name
(10S,11S,14S,15S)-14-hydroxy-14,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1,6,16-trien-5-one
SMILES
[H][C@@]12CC[C@](C)(O)[C@@]1(C)C=CC1=C3CCC(=O)C=C3CC[C@@]21[H]
Độ hòa tan
3.32e-02 g/l
logP
2.53
logS
-3.9
pKa (strongest acidic)
18.9
pKa (Strongest Basic)
-0.53
PSA
37.3 Å2
Refractivity
86.29 m3·mol-1
Polarizability
32.9 Å3
Rotatable Bond Count
0
H Bond Acceptor Count
2
H Bond Donor Count
1
Physiological Charge
0
Number of Rings
4
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB02998
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=261000
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46505539
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C14257
ChemSpider
http://www.chemspider.com/Chemical-Structure.229099.html
... loading
... loading