Dược Lực Học :
M40403 treatment exerts a protective effect against ischaemia-reperfusion-induced myocardial injury, supporting a key role for superoxide anion in reperfusion injuries.
Cơ Chế Tác Dụng :
M40403 is a low molecular weight, synthetic manganese containing superoxide dismutase mimetic (SODm) that selectively removes superoxide anion.
M40403 is the lead candidate in a unique class of compounds known as
superoxide dismutase (SOD) mimetics. These stable, low molecular weight
compounds mimic the effect of superoxide dismutase, a naturally occurring
enzyme designed to destroy superoxide free radicals present in various
diseases associated with pain and inflammation.
Chỉ Định :
Intended for the treatment of pain and possibly various forms of cancer.