Tìm theo
lymphotoxin beta receptor
Thuốc Gốc
Small Molecule
Lymphotoxin beta receptor is a receptor for lymphotoxin. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes.
Cơ Chế Tác Dụng : Lymphotoxin beta receptor is a receptor for lymphotoxin. The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein encoded by Lymphotoxin beta receptor specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis.
Chỉ Định : Investigated for use/treatment in autoimmune diseases.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05833
Wikipedia
http://en.wikipedia.org/wiki/Lymphotoxin_beta_receptor
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