Tìm theo
L-Threonine
Các tên gọi khác (10 ) :
  • (2S,3R)-(-)-Threonine
  • (2S)-threonine
  • 2-Amino-3-hydroxybutyric acid
  • L-(-)-Threonine
  • L-2-Amino-3-hydroxybutyric acid
  • L-alpha-amino-beta-hydroxybutyric acid
  • L-Threonin
  • L-α-amino-β-hydroxybutyric acid
  • Thr
  • Threonine
Thuốc Gốc
Small Molecule
CAS: 72-19-5
ĐG : Hospira Inc. , http://www.hospira.com
CTHH: C4H9NO3
PTK: 119.1192
An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C4H9NO3
Phân tử khối
119.1192
Monoisotopic mass
119.058243159
InChI
InChI=1/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3+/s2
InChI Key
InChIKey=AYFVYJQAPQTCCC-FGNFWGHYNA-N
IUPAC Name
(2S,3R)-2-amino-3-hydroxybutanoic acid
Traditional IUPAC Name
L-threonine
SMILES
C[C@@H](O)[C@H](N)C(O)=O
Độ tan chảy
256 dec °C
Độ hòa tan
9.7E+004 mg/L (at 25 °C)
logP
-2.94
logS
-0.09
pKa (strongest acidic)
2.21
pKa (Strongest Basic)
9
PSA
83.55 Å2
Refractivity
26.46 m3·mol-1
Polarizability
11.08 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
4
H Bond Donor Count
3
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Rule of Five
true
pKa
5.60
Dược Lực Học : L-Threonine is an essential amino acid that helps to maintain the proper protein balance in the body. It is important for the formation of collagen, elastin, and tooth enamel, and aids liver and lipotropic function when combined with aspartic acid and methionine.
Cơ Chế Tác Dụng : An essential amino acid occurring naturally in the L-form, which is the active form. It is found in eggs, milk, gelatin, and other proteins. [PubChem] L-Threonine is a precursor to the amino acids glycine and serine. It acts as a lipotropic in controlling fat build-up in the liver. May help combat mental illness and may be very useful in indigestion and intestinal malfunctions. Also, threonine prevents excessive liver fat. Nutrients are more readily absorbed when threonine is present.
Dược Động Học :

▧ Metabolism :
Hepatic
Chỉ Định : L-Threonine makes up collagen, elastin, and enamel protein. It aids proper fat metabolism in the liver, helps the digestive and intestinal tracts function more smoothly, and assists in metabolism and assimilation.
Dữ Kiện Thương Mại
Giá thị trường
  • Biệt dược thương mại : L-threonine crystal
    Giá bán buôn : USD >4.57
    Đơn vị tính : g
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00156
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00188
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00041
PharmGKB
http://www.pharmgkb.org/drug/PA451673
Wikipedia
http://en.wikipedia.org/wiki/L-Threonine
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