Tìm theo
L-Serine
Các tên gọi khác (19 ) :
  • (2S)-2-amino-3-Hydroxypropanoic acid
  • (S)-(-)-Serine
  • (S)-(−)-serine
  • (S)-2-Amino-3-hydroxypropanoic acid
  • (S)-alpha-Amino-beta-hydroxypropionic acid
  • (S)-Serine
  • beta-Hydroxy-L-alanine
  • beta-Hydroxyalanine
  • L-(-)-Serine
  • L-(−)-serine
  • L-2-Amino-3-hydroxypropionic acid
  • L-3-Hydroxy-2-aminopropionic acid
  • L-3-Hydroxy-alanine
  • L-Ser
  • L-Serin
  • L-Serine
  • S
  • Ser
  • Serine
Thực phẩm chức năng
Thuốc Gốc
Small Molecule
CAS: 56-45-1
ĐG : Spectrum Pharmaceuticals , http://www.spectrumpharm.com
CTHH: C3H7NO3
PTK: 105.0926
A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C3H7NO3
Phân tử khối
105.0926
Monoisotopic mass
105.042593095
InChI
InChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChI Key
InChIKey=MTCFGRXMJLQNBG-REOHCLBHSA-N
IUPAC Name
(2S)-2-amino-3-hydroxypropanoic acid
Traditional IUPAC Name
L-serine
SMILES
N[C@@H](CO)C(O)=O
Độ tan chảy
228 dec °C
Độ hòa tan
4.25E+005 mg/L (at 25 °C)
logP
-3.07
logS
0.66
pKa (strongest acidic)
2.03
pKa (Strongest Basic)
8.93
PSA
83.55 Å2
Refractivity
22.04 m3·mol-1
Polarizability
9.39 Å3
Rotatable Bond Count
2
H Bond Acceptor Count
4
H Bond Donor Count
3
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Rule of Five
true
pKa
2.21 (at 25 °C)
Dược Lực Học : Serine is classified as a nutritionally non-essential amino acid. Serine is critical for the production of the body's proteins, enzymes and muscle tissue. Serine is needed for the proper metabolism of fats and fatty acids. It also helps in the production of antibodies. Serine is used as a natural moisturizing agent in some cosmetics and skin care products. The main source of essential amino acids is from the diet, non-essential amino acids are normally synthesize by humans and other mammals from common intermediates.
Cơ Chế Tác Dụng : A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from glycine or threonine. It is involved in the biosynthesis of purines; pyrimidines; and other amino acids. [PubChem] L-Serine plays a role in cell growth and development (cellular proliferation). The conversion of L-serine to glycine by serine hydroxymethyltransferase results in the formation of the one-carbon units necessary for the synthesis of the purine bases, adenine and guanine. These bases when linked to the phosphate ester of pentose sugars are essential components of DNA and RNA and the end products of energy producing metabolic pathways, ATP and GTP. In addition, L-serine conversion to glycine via this same enzyme provides the one-carbon units necessary for production of the pyrimidine nucleotide, deoxythymidine monophosphate, also an essential component of DNA.
Chỉ Định : Used as a natural moisturizing agent in some cosmetics and skin care products.
Dữ Kiện Thương Mại
Giá thị trường
  • Biệt dược thương mại : L-serine powder
    Giá bán buôn : USD >3.85
    Đơn vị tính : g
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00133
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00065
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00016
PharmGKB
http://www.pharmgkb.org/drug/PA451330
Wikipedia
http://en.wikipedia.org/wiki/Serine
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