Tìm theo
L-Proline
Các tên gọi khác (21 ) :
  • (-)-(S)-Proline
  • (-)-2-Pyrrolidinecarboxylic acid
  • (-)-Proline
  • (−)-(S)-proline
  • (−)-2-pyrrolidinecarboxylic acid
  • (−)-proline
  • (2S)-Pyrrolidine-2-carboxylic acid
  • (S)-2-Carboxypyrrolidine
  • (S)-2-Pyrrolidinecarboxylic acid
  • (S)-Pyrrolidine-2-carboxylic acid
  • 2-Pyrrolidinecarboxylic acid
  • L-(-)-Proline
  • L-alpha-pyrrolidinecarboxylic acid
  • L-Prolin
  • L-Proline
  • L-pyrrolidine-2-carboxylic acid
  • L-α-pyrrolidinecarboxylic acid
  • P
  • Prolina
  • PROLINE
  • Prolinum
Thực phẩm chức năng
Thuốc Gốc
Small Molecule
CAS: 147-85-3
ĐG : Professional Co.
CTHH: C5H9NO2
PTK: 115.1305
A non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons. [PubChem]
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C5H9NO2
Phân tử khối
115.1305
Monoisotopic mass
115.063328537
InChI
InChI=1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
InChI Key
InChIKey=ONIBWKKTOPOVIA-BYPYZUCNSA-N
IUPAC Name
(2S)-pyrrolidine-2-carboxylic acid
Traditional IUPAC Name
L-proline
SMILES
OC(=O)[C@@H]1CCCN1
Độ tan chảy
221 dec °C
Độ hòa tan
1.62E+005 mg/L (at 25 °C)
logP
-2.54
logS
0.5
pKa (strongest acidic)
1.94
pKa (Strongest Basic)
11.33
PSA
49.33 Å2
Refractivity
28.06 m3·mol-1
Polarizability
11.5 Å3
Rotatable Bond Count
1
H Bond Acceptor Count
3
H Bond Donor Count
2
Physiological Charge
0
Number of Rings
1
Bioavailability
1
Rule of Five
true
Dược Lực Học : L-Proline is a major amino acid found in cartilage and is important for maintaining youthful skin as well as repair of muscle, connective tissue and skin damage. It is also essential for the immune system, and for necessary balance of this formula. It is an essential component of collagen and is important for proper functioning of joints and tendons. L-Proline is extremely important for the proper functioning of joints and tendons. Helps maintain and strengthen heart muscles.
Cơ Chế Tác Dụng : A non-essential amino acid that is synthesized from glutamic acid. It is an essential component of collagen and is important for proper functioning of joints and tendons. [PubChem] Glycogenic, by L-Proline oxidase in the kidney, it is ring-opened and is oxidized to form L-Glutamic acid. L-Ornithine and L-Glutamic acid are converted to L-Proline via L-Glutamic acid-gamma-semialdehyde. It is contained abundantly in collagen, and is intimately involved in the function of arthrosis and chordae.
Dược Động Học :

▧ Metabolism :
Hepatic
Chỉ Định : L-Proline is extremely important for the proper functioning of joints and tendons and also helps maintain and strengthen heart muscles.
Dữ Kiện Thương Mại
Giá thị trường
  • Biệt dược thương mại : L-proline crystal
    Giá bán buôn : USD >3.6
    Đơn vị tính : g
Đóng gói
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00172
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=145742
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46506858
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00148
KEGG Drug
http://www.genome.jp/dbget-bin/www_bget?drug:D00035
ChemSpider
http://www.chemspider.com/Chemical-Structure.128566.html
PharmGKB
http://www.pharmgkb.org/drug/PA451125
Wikipedia
http://en.wikipedia.org/wiki/L-Proline
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