Tìm theo
L-Asparagine
Các tên gọi khác (16 ) :
  • (2S)-2-amino-3-carbamoylpropanoic acid
  • (2S)-2,4-diamino-4-oxobutanoic acid
  • (S)-2-amino-3-carbamoylpropanoic acid
  • (S)-Asparagine
  • 2-Aminosuccinamic acid
  • alpha-aminosuccinamic acid
  • Asn
  • Asparagine
  • Aspartamic acid
  • L-2-aminosuccinamic acid
  • L-Asparagin
  • L-Asparagine
  • L-aspartic acid beta-amide
  • L-aspartic acid β-amide
  • N
  • α-aminosuccinamic acid
dietary supplements, micronutrients, supplements, non essential amino acids
Thuốc Gốc
Small Molecule
CAS: 70-47-3
CTHH: C4H8N2O3
PTK: 132.1179
A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed)
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C4H8N2O3
Phân tử khối
132.1179
Monoisotopic mass
132.053492132
InChI
InChI=1S/C4H8N2O3/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H2,6,7)(H,8,9)/t2-/m0/s1
InChI Key
InChIKey=DCXYFEDJOCDNAF-REOHCLBHSA-N
IUPAC Name
(2S)-2-amino-3-carbamoylpropanoic acid
Traditional IUPAC Name
L-asparagine
SMILES
N[C@@H](CC(N)=O)C(O)=O
Độ tan chảy
234-235 °C
Độ hòa tan
2.94E+004 mg/L (at 25 °C)
logP
-3.82
logS
-0.74
pKa (strongest acidic)
2
pKa (Strongest Basic)
8.43
PSA
106.41 Å2
Refractivity
28.35 m3·mol-1
Polarizability
11.68 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
4
H Bond Donor Count
3
Physiological Charge
0
Number of Rings
0
Bioavailability
1
Rule of Five
true
pKa
8.82 (at 18 °C)
Dược Lực Học : A non-essential amino acid. Asparagine is critical for the production of the body's proteins, enzymes and muscle tissue. Supplements of this amino acid are claimed to balance nervous system function.
Cơ Chế Tác Dụng : A non-essential amino acid that is involved in the metabolic control of cell functions in nerve and brain tissue. It is biosynthesized from aspartic acid and ammonia by asparagine synthetase. (From Concise Encyclopedia Biochemistry and Molecular Biology, 3rd ed) Asparagine, a non-essential amino acid is important in the metabolism of toxic ammonia in the body through the action of asparagine synthase which attaches ammonia to aspartic acid in an amidation reaction. Asparagine is also used as a structural component in many proteins.
Chỉ Định : Used for nutritional supplementation, also for treating dietary shortage or imbalance.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB00174
PubChem Compound
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=6267
PubChem Substance
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=46507804
KEGG Compound
http://www.genome.jp/dbget-bin/www_bget?cpd:C00152
ChemSpider
http://www.chemspider.com/Chemical-Structure.6031.html
PharmGKB
http://www.pharmgkb.org/drug/PA164776968
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