Tìm theo
ISA247
Các tên gọi khác (1) :
  • trans-ISA247
antipsoriatic agents
Thuốc Gốc
Small Molecule
CAS: 515814-00-3
ISA247 is a novel cyclosporine analog. It is an immunosuppressive compound currently being investigated for the treatment of psoriasis and for the prevention of organ rejection in kidney transplant patients. All studies to date suggest that ISA247 is more potent and less toxic than currently available treatments within the drug class of calcineurin inhibitors.
Cơ Chế Tác Dụng : ISA247 is a novel cyclosporine analog. It is an immunosuppressive compound currently being investigated for the treatment of psoriasis and for the prevention of organ rejection in kidney transplant patients. All studies to date suggest that ISA247 is more potent and less toxic than currently available treatments within the drug class of calcineurin inhibitors. ISA247 inhibits calcineurin. As a consequence, it inhibits T cell activation by blocking the transcription of early cytokines.
Chỉ Định : Investigated for use/treatment in autoimmune diseases, eye disorders/infections, immunosuppressive, kidney transplant surgery, psoriasis and psoriatic disorders, rheumatoid arthritis, and transplant (rejection).
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB04906
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