Tìm theo
intranasal apomorphine
Thuốc Gốc
Small Molecule
Intranasal apomorphine is a nasal formulation of apomorphine developed by Nastech Pharmaceutical Co Inc for the potential treatment of erectile dysfunction and female sexual dysfunction.
Cơ Chế Tác Dụng : Intranasal apomorphine is a nasal formulation of apomorphine developed by Nastech Pharmaceutical Co Inc for the potential treatment of erectile dysfunction and female sexual dysfunction. Intranasal apomorphine is a potent dopamine agonist that promotes erectile function by stimulating receptors in the hypothalamus. The PDE-5 inhibitor class of erectile dysfunction (ED)therapies does not function in the brain but only on the final step in erectile function. In addition, unlike the class of PDE-5 inhibitors that produce hypotension, headaches, and other side effects due to non-specific interactions in the body, apomorphine acts specifically on the D1/D2 class of dopamine receptors that are responsible for the initiation of the erectile response in the brain.
Chỉ Định : Investigated for use/treatment in erectile dysfunction and sexual dysfunction (female).
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05816
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