Tìm theo
Indalpine
Thuốc Gốc
Small Molecule
CAS: 63758-79-2
CTHH: C15H20N2
PTK: 228.3327
Indalpine was one of the first selective serotonin reuptake inhibitors to reach the American market. It was initially marketed by Pharmuka. However, after the emergence of widespread concern regarding adverse effects caused by SSRIs, and reported hematological effects caused by Indalpine, it was abruptly withdrawn from the US market.
Nhận Dạng Quốc Tế & Đặc Tính Hóa Học
Công thức hóa học
C15H20N2
Phân tử khối
228.3327
Monoisotopic mass
228.16264865
InChI
InChI=1S/C15H20N2/c1-2-4-15-14(3-1)13(11-17-15)6-5-12-7-9-16-10-8-12/h1-4,11-12,16-17H,5-10H2
InChI Key
InChIKey=SADQVAVFGNTEOD-UHFFFAOYSA-N
IUPAC Name
3-[2-(piperidin-4-yl)ethyl]-1H-indole
Traditional IUPAC Name
indalpine
SMILES
C(CC1=CNC2=CC=CC=C12)C1CCNCC1
Độ tan chảy
167
Độ hòa tan
1.25e-02 g/l
logP
3.07
logS
-4.3
pKa (strongest acidic)
17.32
pKa (Strongest Basic)
10.36
PSA
27.82 Å2
Refractivity
71.77 m3·mol-1
Polarizability
27.59 Å3
Rotatable Bond Count
3
H Bond Acceptor Count
1
H Bond Donor Count
2
Physiological Charge
1
Number of Rings
3
Bioavailability
1
Rule of Five
true
Ghose Filter
true
Dữ Kiện Thương Mại
Nhà Sản Xuất
  • Công ty : Pharmuka
    Sản phẩm biệt dược : Upstène
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB08953
Wikipedia
http://en.wikipedia.org/wiki/Indalpine
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