Tìm theo
IMC-11F8
Thuốc Gốc
Small Molecule
IMC-11F8 is a fully human IgG1 monoclonal antibody that blocks the ligand binding site of EGFR that is involved in triggering and regulating the malignant growth of many EGFR-expressing epithelial tumors. IMC-11F8 is developed for the treatment of advanced colorectal cancer.
Cơ Chế Tác Dụng : IMC-11F8 is a fully human IgG1 monoclonal antibody that blocks the ligand binding site of EGFR that is involved in triggering and regulating the malignant growth of many EGFR-expressing epithelial tumors. IMC-11F8 is developed for the treatment of advanced colorectal cancer. IMC-11F8 is a fully human monoclonal antibody that is designed to bind to the EGFR, thereby inhibiting certain ligands known as growth factors from binding to and activating the receptor. This action blocks a signal pathway key to tumor growth and repair and has also been shown to induce cell death, or apoptosis, in human tumors in animal models.
Chỉ Định : Investigated for use/treatment in colorectal cancer.
Tài Liệu Tham Khảo Thêm
drugbank
http://www.drugbank.ca/drugs/DB05774
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