IC41

Thuốc Gốc

Biotech

IC41 is a therapeutic peptide vaccine. It is being devloped by Intercell AG for the treatment of hepatitis C. The vaccine consists of five synthetic peptides (IPEP83, 84, 87, 89,1426) harboring HCV CD4 and CD8 T-cell epitopes and the synthetic adjuvant poly-L-arginine.

Dược Lực Học : IC41 is able of inducing a significant proliferative response in chronic HCV patients. IC41 can induce interferon gamma secreting T-cells in chronic HCV patients. Interferon gamma secretion is a hallmark of type I T-cell responses. Such responses are seen during the acute phase of infection in the subset of HCV patients, who eliminate the virus and do not proceed to chronic infection. Induction of type I T-cell responses as achieved by IC41 is a primary goal of therapeutic vaccination against HCV.

Chỉ Định : Investigated for use/treatment in hepatitis (viral, C).

Tài Liệu Tham Khảo Thêm

drugbank

http://www.drugbank.ca/drugs/DB05776

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